How does Dapoxetine work?
Dapoxetine works by increasing the action of the neurotransmitter Serotonin at the postsynaptic left and promotes ejaculatory delay. It belongs to the class of medications known as Selective Serotonin Reuptake Inhibitors (SSRIs). Initially created as an antidepressant, this medicine gets absorbed and eliminated rapidly in the body. Thus, the fast-acting property of Dapoxetine makes it suitable for the treatment of premature ejaculation but not as an antidepressant.
It prolongs intravaginal ejaculation latency time (IELT) and increases the sense of control and sexual satisfaction in men.
Uses of this tablet
Dapoxetine has been approved for the treatment of premature ejaculation (PE) in men. The different dosages impact differently and improve the mean IELT significantly. Since it gets rapidly absorbed and eliminated in the body, its pharmacokinetics make it favorable to minimize drug accumulation in the body, habituation, and certain side-effects.
Dapoxetine is meant to be taken orally with water. It comes in two dosages, namely 30 mg and 60 mg. For men with lifelong PE, Dapoxetine 60 mg improves the time of ejaculation significantly as compared to the 30 mg dose. This medicine is intended to be taken 1-3 hours before any sexual activity. You should not consume more than one tablet in 24 hours. This medicine can be taken with or without food. Since it has a bitter taste, it should be swallowed without chewing.
Make sure that you follow your doctor’s prescription carefully to achieve the desired results of the medication.
Some common side-effects of Dapoxetine include:
- Dry mouth
- Excessive sweating
- Feeling confused
- Increased blood pressure
If any of these side-effects persist for long, contact your doctor immediately.
Before Taking This Medicine
Dapoxetine may not be suitable for you if you have certain conditions. Before you take this medicine, let your doctor know:
- If you have a tendency to faint.
- If you are suffering from heart disease or have a history of stroke, congestive heart failure.
- If you have a bleeding or clotting disorder such as hemophilia.
- If you have mental health issues or mood disorders such as bipolar disorder, depression, etc.
- If you have epilepsy.
- If you have a kidney or liver disease.
- If you have an eye-related condition such as glaucoma.
- If you have allergies to certain medications.
If you take any medicines for existing health conditions or for any other purposes, let your doctor know about them. Following is the list of drugs that should not be taken in combination with Dapoxetine:
- CYP3A4 inhibitors such as ketoconazole, ritonavir, and telithromycin
- Monoamine oxidase inhibitors (MAOIs)
- Selective Serotonin Reuptake Inhibitors (SSRIs)
- Serotonin-norepinephrine Reuptake Inhibitors
Interaction with alcohol
Consumption of alcohol whilst taking this medicine should be avoided. It increases the sedative effects of alcohol and also increases the risk of fainting.
Interaction with grapefruit juice
Grapefruit juice can increase the amount of this medicine in the bloodstream. This increases the risk of side-effects. Therefore, a person should avoid taking dapoxetine for the next 24 hours if he drinks grapefruit juice.
Important Storage Instructions
- Keep these tablets out of reach and sight of children.
- Store these tablets in a cool, dry place, and away from direct heat, moisture, and light.
- Do not consume the medication after its expiration date.
Frequently Asked Questions (FAQs)
Is it safe to take Dapoxetine?
Ans. Dapoxetine is the very first drug developed for safe and effective treatment of premature ejaculation (PE) in men. Unlike other SSRIs that are mainly used as an antidepressant, dapoxetine gets rapidly absorbed and eliminated in the body to provide ejaculatory control.
How long does it take for this medicine to work?
Ans. This medicine is intended to be taken 1-3 hours before sexual activity. Its maximum plasma concentration is reached 1-2 hours after it is administered orally.
Can I take Dapoxetine with Viagra?
Ans. Dapoxetine can be taken with Viagra only after a prescription from the doctor. Taking the two medicines together improves ejaculation time and the quality of erections in men suffering from erectile dysfunction (ED). The pharmacokinetics of the two medicines do not get altered when they’re taken together.
What happens if I miss a dose?
Ans. This medicine is taken as and when needed. Therefore, it is highly unlikely that you’ll miss a dose. This medicine is not meant to be taken daily. Therefore, you should only take it before you anticipate having sex.
Which is better, Paroxetine, or Dapoxetine?
Ans. Dapoxetine is a novel effective treatment for premature ejaculation (PE) in men. While a lower dose such as 30 mg may not outperform the effects of Paroxetine, a 60 mg dose increases the intravaginal ejaculation latency time (IELT) significantly when compared to paroxetine.